Jane McHowat, Ph.D.

Position: Untitled document


My Lab

Untitled document Bath University, Ph.D, 1988

Office: Untitled document Schwitalla Hall

Email Address: mchowaj@slu.edu

CV: Jane McHowat, Ph.D.

Jane McHowat, Ph.D.
Jane McHowat, Ph.D.
Clinical/Research Interests:
Untitled document Please see lab website for information.

Untitled document



Fellow of the American Heart Association
American Physiological Society

Departmental Affiliations



1.  Rastogi, P., McHowat, J. Inhibition of calcium independent phospholipase A2 prevents inflammatory mediator production in pulmonary microvascular endothelium.  Resp. Physiol. Neurobiol.  2009; 165, 167-174 PMC2845306

2.  Sharma, J., Rastogi, P., Creer, M.H., McHowat, J. Polymorphonuclear leukocytes isolated from umbilical cord blood are a useful research tool to study adherence to cell monolayers, J. Immunol. Methods 2009; 351, 30-35  PMC2783264

3.  Rastogi, P., Sharma, J., McHowat, J. Methods for measuring the activity and expression of phospholipases A2.  In:  Methods in Lipid-Mediated Signaling.  Murphy E & Rosenberger T (eds)  Taylor & Francis. 2010; pages 4-26

4.  Sharma, J., Turk, J., McHowat, J. Endothelial cell prostaglandin I2 and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A2β knockout mouse.  Biochemistry, 2010; 49, 5473-5481  PMC2938187

5.  Rastogi, P., Rickard, A., Klumpp, D.J., McHowat, J. Urothelial cell platelet-activating factor production is mediated via calcium-independent phospholipase A2γ.  Urology. 2011; 77, 248.e1-7.

6.  Sharma, J., Turk, J., Mancuso D.J., Sims, H.F., Gross, R.W., McHowat, J. Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells of wild type and knockout mice.  Am J Physiol Cell Physiol. 2011; 300, C872-C879.  PMID: 21191104

7.  McHowat, J., Gullickson G., Hoover, R.G., Sharma J., Turk, J., Kornbluth J.  Platelet-activating factor and metastasis:  Calcium-independent phospholipase A2β deficiency protects against breast cancer metastasis to the lung.  Am J Physiol Cell Physiol. 2011; 300,C825-C832  PMID:21228317

8.  Sharma, J., McHowat, J. PGE2 release from tryptase-stimulated rabbit ventricular myocytes is mediated by calcium-independent phospholipase A2γ, Lipids, 2011; 46, 391-397. PMID:21461868

9. Blum, J., Kinsey, G.R., Monian, P., Sun, B., Cummings, B.S., McHowat, J., Schnellmann, R.G.  Profiling of Fatty Acids Released During Calcium-induced Mitochondrial Permeability Transition in Isolated Rabbit Kidney Cortex Mitochondria.  Toxicol In Vitro. 2011; 25. 1001-6. PMID: 21443943

Honors and Awards

De Montfort University, B. Sc. (First Class Honors) Pharmacy
University of Bath, Ph. D. Pharmacology    
1984-1987  Science and Engineering Research Council Predoctoral Fellowship
1991-1993  American Heart Association, Missouri Affiliate Postdoctoral Fellowship
1996-2000  Public Health Service, NHLBI FIRST Award
2011 Fellow of the American Heart Association

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Modified Date:Wednesday 19-Apr-17 13:54:03 CDT

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