Research Microscopy and Histology Core


The Research Microscopy & Histology Core provides a wide range of histological and microscopy services on a fee-for-service basis to researchers at Saint Louis University and at other universities and businesses around the world.  Services provided include the following:

  • Fixation and processing of samples into paraffin, OCT, and plastic
  • Sectioning of tissue blocks for LM histology and EM ultrastructure
  • Staining of thick and thin sections for LM and EM
  • Routine and special histological stains
  • Bright field, phase contrast and differential interference contrast light microscopy
  • Epi-fluorescence microscopy
  • Laser scanning confocal microscopy
  • Live animal scanning confocal microscopy
  • Transmission electron microscopy
  • Scanning electron microscopy
  • Live cell and time lapse cell motility studies
  • Laser capture microscopy
  • Elemental analysis by EDAX
  • Negative staining for EM
  • Quantitative morphometry
  • Immuno-histochemistry on paraffin and frozen sections for light microscopy
  • Immuno-fluorescence on paraffin sections for epi-fluorescence and scanning confocal microscopy
  • Immuno-gold cytochemistry on thin plastic sections for EM
  • Processing, organizing and labeling micrographs for publications, abstracts, seminars and grant proposals
  • Training technicians, students, post-docs, and faculty in the techniques of research microscopy

Consultation and Rapid Turn-Around Time

The Research Microscopy & Histology Core is well equipped for all types of microscopy-related techniques and services.  The technical staff will assist researchers in planning experiments, working at the microscopes, and evaluating results.  We will also carry out entire microscopy projects from start to finish, concluding with a written report with illustrations and a summary of the results.  We are sensitive to the importance of getting results back to the researcher as quickly as possible and we endeavor to maintain the shortest turn-around-times consistent with sample volume and complexity.