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Research Microscopy Core

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RESEARCH MICROSCOPY CORE

                                                                     DEPARTMENT OF PATHOLOGY

RESEARCH MICROSCOPY AND CONFOCAL CORES

The Research Microscopy and Confocal Cores provide a wide range of histological and microscopy services on a fee-for-service basis to researchers at Saint Louis University and at other universities and businesses around the world. Services provided include the following:

  • fixation and processing of samples into paraffin, OCT or plastic
  • sectioning of tissue blocks for LM histology or EM ultrastructure
  • staining of thick or thin sections for LM and EM
  • bright field, phase contrast and differential interference contrast light microscopy
  • epi-fluorescence microscopy
  • transmission and scanning electron microscopy
  • elemental analysis by EDAX
  • negative staining for EM
  • quantitative morphometry
  • cryo-ultramicrotomy
  • freeze fracture
  • immuno-histochemistry on thick plastic or paraffin sections for light microscopy
  • immuno-gold cytochemistry on thin plastic or thin frozen sections for EM
  • digitizing, processing, organizing and labeling micrographs for publications, abstracts, seminars and grant proposals
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Consultation and Rapid Turn-Around Time

The technical staff will assist researchers in planning experiments and evaluating results, and will either assist researchers at the microscopes or will carry out projects for researchers depending on the needs of the investigator. Rapid turn-around times are crucial for the timely progression of research projects; we usually have results back within 2 weeks on small projects (4-5 samples) and within 4-5 weeks on large (50-100 sample) projects. The Research Microscopy and Confocal Cores are exceptionally well-equipped for virtually all types of microscopy-related techniques and services.

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