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Division of Nephrology and Hypertension

Saint Louis University School of Medicine's Division of Nephrology and Hypertension treats patients with high blood pressure, and acute and chronic disorders of the kidney and urinary tract.

Department faculty pose for a group photo in the hallway of a SLU School of Medicine building.
 

Expert Care for Kidneys and Blood Pressure

The Division of Nephrology and Hypertension is dedicated to researching, treating and preventing kidney diseases and hypertension. Its nationally recognized services include:

  • Dialysis
  • Critical care
  • Renal replacement therapies
  • Evaluation for kidney transplant
  • Kidney biopsy
  • Interventional nephrology
  • Advanced hypertension management

Division nephrologists provide outpatient care at two dedicated specialty clinics: a Medicare-certified dialysis clinic on the Saint Louis University campus, and a hypertension clinic where patients acquire tools and strategies to manage blood pressure. 

The division is also known for its world-class fellowship program that boasts more than 100 graduates since its inception more than 30 years ago. 

Meet the Faculty

Nephrology and Hypertension Research

Division researchers focus on clinical trials and a wide spectrum of kidney functions and diseases, though they are known for kidney transplantation research — particularly how genetic factors affect transplant outcomes. 

Research Areas
  • Role of CLIC4 in angiogenesis
  • Ion channel activity of ApoL1 and its kidney disease-associated variants
  • Channel activity of ApoL1 and progressive chronic kidney disease
  • Ion channel activity of ApoL1 and podocyte injury
  • Cost-effectiveness of reducing knowledge barriers to increase living kidney donor transplants
  • Interventions to increase pancreas utilization
  • Effect of nutrition education on dialysis patients' phosphorus and iPTH levels
  • Regulation of nephron progenitor cell self-renewal and differentiation
  • Regulation of renal progenitor cell fate in normal kidney development and Townes-Brocks syndrome
  • Identifying genetic causes of congenital renal disease
  • Treating kidney fibrosis with RGD integrin antagonists
  • Effects of APOL1 on gestational hypertension, low birth weight and prematurity
  • Long-term health outcomes of African American live kidney donors
  • Choosing immune suppression in renal transplantation by efficacy and morbidity
  • Open-label, prospective, randomized, multi-center, Phase II comparative trial of Thymoglobulin versus Simulect for the prevention of delayed graft function and acute allograft rejection in renal allograft recipients
  • Liver transplantation: patient-reported outcomes, healthcare cost and comparative modeling of the simultaneous liver-kidney allocation policy
  • Modifiable factors affecting live donor disparities
  • Economic strategies to reduce organ discard through risk-adjusted payment mechanisms
  • Central artery pressures and waveform analysis in gestational hypertension and preeclampsia
  • Volume dependency of arterial stiffness
  • Randomized, multi-country, multicenter, double-blind, parallel, placebo-controlled study of the effects of Atrasentan on renal outcomes in subjects with type 2 diabetes and nephropathy  
  • Pathophysiological mechanisms of cardiorenal syndrome with an emphasis on novel treatments targeting bidirectional signaling pathways