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Daniel F. Hoft, M.D., Ph.D.

Professor; Director, Division of Infectious Diseases, Allergy and Immunology; Dianna and J. Joseph Adorjan Endowed Chair of Infectious Diseases and Immunology; Director, Center for Vaccine Development; Director, Institute for Vaccine Science and Policy;
Department of Internal Medicine

Courses Taught

Epidemiology, pathogenesis, diagnosis, treatment and prevention of Tuberculosis: lectures to first- and second-year medical students (1996-present); Effector T cells: core biomedical graduate student lecture (1999-2015); Medical Parasitology: lectures to first-year medical students (1994-2018)

Education

Ph.D., microbiology/immunology
University of Iowa Hospitals and Clinics (1992)

Fellowship
University of Iowa Hospitals and Clinics

Residency
University of Iowa Hospitals and Clinics

Medical School
University of Missouri-Columbia School of Medicine (1985)

B.A., Chemistry
Grinnell College, Grinnell, Iowa (1977)

Practice Areas

  • Clinical research
  • Infectious diseases

Research Interests

  • Director, Center for Vaccine Development
  • Role of TB-specific human gamma/delta T cells in vaccine-induced immunity
  • Universal influenza T cell targeted vaccines
  • Development of a Human Intradermal (ID) BCG Challenge Model
  • Roles for CD4+ Th9 and other immune subsets in mucosal and systemic TB immunity
  • Pandemic urgent clinical trial research

Labs and Facilities

  • DRC-Basement: Animal model research on TB influenza
  • CVD-DRC-1: Vaccine center clinic - clinical vaccine and treatment and Chajas DTE
  • DRC-8: Basic science and vaccinology labs

Publications and Media Placements

  • Lancet
  • Vaccine
  • PLoS Pathogens
  • Journal of Clinical Investigation
  • Nature Medicine

Honors and Awards

  • Award of Merit - St. Louis Metropolitan Medical Soceity (2023)
  • Outstanding Scientist Fellows Award - St. Louis Academy of Science (2018)
  • Dianna and J. Joseph Adorjan Endowed Chair of Infectious Diseases and Immunology - Saint Louis University School of Medicine (2014)
  • NIH Pysician Scientist Training Award (1986-1992)

Professional Organizations and Associations

  • Society of Tropical Medicine and Hygiene
  • American Association of Immunologists
  • Fellow, Infectious Diseases Society of America

Community Work and Service

  • Staffing TB screening clinic for Bosnian immigrants, St. Louis City Health Department (2000-2005)
  • TB Control Committee, American Lunch Association of Eastern Missouri (1996-2010)